The U.S. Department of Health and Human Services, National Institutes of Health (NIH) is seeking applications for its U.S. – India Collaborative Environmental Health Research Program.


The purpose of the United States (U.S.)-India Program for Environmental Health Collaborative Research is to stimulate and promote collaborative basic, translational, and clinical research between U.S.-based researchers and Indian researchers and to gain a comprehensive understanding of the impacts of environmental insults on children and adults across all organ systems (e.g. pulmonary, cardiovascular, cancer, and neurological disorders).

The National Institute of Environmental Health Sciences (NIEHS) and the Indian Council for Medical Research (ICMR) are interested in supporting collaborative research and research training through joint U.S.-India partnerships that address or seek to understand how exposures to toxic environmental insults alter biologic processes and are linked to disease initiation, progression, or morbidity. In addition, both agencies are interested in research that leads to the development of prevention and intervention strategies to reduce environmentally induced diseases.

To promote these collaborative efforts from the outset, the partnering U.S. and Indian investigators must work jointly to submit identical applications to NIH and the Indian Council of Medical Research (ICMR), respectively.

Research Objectives

  • This FOA is intended to support collaborative research and research training through joint U.S.-India partnerships that address or seek to promote understanding how exposures to toxic environmental insults, specifically air pollution and its component chemicals (or the mixture of chemicals and other exposures that combined are considered air pollution), alter biologic processes and are linked to disease initiation, progression, or morbidity. These exposures include particulate matter of different sizes (PM10, PM2.5, and ultrafine particles) and composition, chemicals such as Ozone, NO, SO, and air toxics such as metals, dust, airborne agriculture pesticides as well as PAHs and other combustion by-products due to crop burning. In addition, NIEHS and ICMR are interested in research that leads to the development of prevention and intervention strategies to reduce environmentally induced diseases.
  • Applications may include collaborative research projects aimed at addressing the following areas of research relevant to the mission of the NIEHS including, but not limited to:
    • Ambient air pollution from different sources and their multi-organ system health effects assessed from fundamental, epidemiological, or clinical research settings
    • Epidemiological or clinical studies on children or adults as well as relevant animal models to understand impact of PM2.5 on pulmonary, cardiovascular, cancer, and neurological systems
    • Impact of ambient air pollutants on preexisting disease conditions such as asthma, COPD, cancer, cardiovascular, diabetes, obesity, and neurological disorders
    • Development, validation and use of multiple modalities for improved exposure assessment at the community, population and personal level
    • Multi-city epidemiological studies in highly polluted communities including panel studies in children and adults
    • Physicochemical characterization of ambient particulates (PM10, PM2.5) from diverse cities and communities representing geographical regions and associated health outcomes
    • Molecular and biochemical studies in relevant animal models to predict cardiopulmonary, vascular, and developmental effects
    • Early life exposures to air pollutants and their biological consequences including genetic and disease susceptibility
    • Exposures before and during pregnancy and the effects on mothers and offspring
    • Validation of new technology for improving air pollution monitoring
    • Interventions to reduce national, regional and community-wide exposures to geographic areas
    • Interventions in vulnerable populations that reduce the personal level of exposure to air pollution and mitigate the health effects
  • This FOA requires that the collaboration between the U.S. and Indian research teams be submitted as a Multiple Principle Investigator (Multi-PD/PI) application with both of the lead scientists from each country as the PD/PI. Applications may be derived from existing collaborations with an established history of interaction, or from new partnerships developed in response to this FOA.
  • The collaboration must be based on interactive relationships that maximize the expertise of the individual U.S. and Indian research teams. In addition to research, there will be opportunities for the graduate students/postdocs/junior scientists in India and the US to visit the laboratories of collaborators for a short period (6- 8 weeks) once a year.

Funding Information

  • NIEHS intends to commit $1,000,000 in FY 2021 to fund 4-5 awards.
  • Application budgets are limited to $200,000 direct costs per year. Budget costs must reflect the actual needs of the proposed project.

Duration

The project period is limited to 5 years.

Eligibility Criteria

  • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education
    • The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
      • Hispanic-serving Institutions
      • Historically Black Colleges and Universities (HBCUs)
      • Tribally Controlled Colleges and Universities (TCCUs)
      • Alaska Native and Native Hawaiian Serving Institutions
      • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Nonprofits Other Than Institutions of Higher Education
    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • For-Profit Organizations
    • Small Businesses
    • For-Profit Organizations (Other than Small Businesses)
  • Governments
    • State Governments
    • County Governments
    • City or Township Governments
    • Special District Governments
    • Indian/Native American Tribal Governments (Federally Recognized)
    • Indian/Native American Tribal Governments (Other than Federally Recognized)
    • Eligible Agencies of the Federal Government
    • U.S. Territory or Possession
  • Other
    • Independent School Districts
    • Public Housing Authorities/Indian Housing Authorities
    • Native American Tribal Organizations (other than Federally recognized tribal governments)
    • Faith-based or Community-based Organizations
    • Regional Organizations
  • Foreign Institutions
    • Only foreign components from India are eligible
    • Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
    • Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

For more information, visit Grants.gov.

Name of the Organisation
National Institutes of Health (NIH)
Location
India
Grant Amount
USD 2,00,000
Closing date of Proposal
Thursday, 15 October, 2020
RFP Email
FBOWebmaster@OD.NIH.GOV
RFP URL
https://www.grants.gov/web/grants/view-opportunity.html?oppId=326640
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